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商品详情：
英文名称：14-3-3 Theta
中文名称：14-3-3 Theta重组兔单克隆抗体
别 名；1433T_HUMAN; YWHAQ; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1;
研究领域；神经生物学 信号转导 细胞凋亡
抗体来源；Rabbit
克隆类型；Monoclonal
交叉反应； (predicted: Human, Mouse, Rat, )
产品应用；WB=1:500-2000 ICC=1:50-100 IF=1:50-100
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量；28kDa
细胞定位；细胞浆
性 状；Liquid
浓 度；1mg/ml
免 疫 原；Recombinant human 14-3-3 Theta protein, full length.
亚 型；IgG
纯化方法；affinity purified by Protein A
缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍； This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Function:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
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