|
产品名称 |
KMT6 / EZH2 (15A18) Rabbit Monoclonal Antibody |
|
英文名称 |
KMT6 / EZH2 (15A18) Rabbit Monoclonal Antibody |
|
类别 |
抗原抗体 |
|
反应种属 |
Human |
|
应用 |
WB |
|
别名 |
EZH1; EZH2; EZH2b; KMT6; KMT6A; |
|
Clonality |
Monoclonal |
|
存储缓冲液 |
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
|
免疫原 |
Recombinant protein of human KMT6/EZH2 |
|
稀释度 |
WB 1:1000 |
|
参考分子量 |
98kDa |
|
预测分子量 |
85kDa |
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运输及保存条件 |
20°C/1 year |
|
Human Gene ID |
2146 |
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基因名称 |
EZH2 |
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蛋白名称 |
KMT6 |
|
宿主 |
Rabbit |
|
同种型 |
LgG |
|
组织表达 |
In the ovary, expressed in primordial follicles and oocytes and also in external follicle cells (at protein level) (PubMed:31451685). Expressed in many tissues (PubMed:14532106) Overexpressed in numerous tumor types including carcinomas of the breast, colon, larynx, lymphoma and testis (PubMed:14532106) |
|
细胞定位 |
Nucleus. Note=Localizes to the inactive X chromosome in trophoblast stem cells. {ECO:0000250|UniProtKB:Q61188} |
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注意事项 |
KMT6 / EZH2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
|
功能 |
Polycomb group (PcG) protein. subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' |
 Rabbit Monoclonal Antibody.jpg)
Western blot detection of KMT6/EZH2 in Hela,A549,HL-60 cell lysates using KMT6/EZH2 antibody(1:1000 diluted).
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively.
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 Rabbit Monoclonal Antibody.jpg)
资料/datasheet
