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MMP17 (19A10) Rabbit Monoclonal Antibody
A-DK10249
MMP17 (19A10) Rabbit Monoclonal Antibody
货号 纯度 规格 目录价 会员价 库存 数量 购买
A-DK10249-50µl 50µl 50µl ¥1200.00 登录查看
A-DK10249-100µl 100µl 100µl ¥2200.00 登录查看
产品详情

产品名称

MMP17 (19A10) Rabbit Monoclonal Antibody

英文名称

MMP17 (19A10) Rabbit Monoclonal Antibody

类别

抗原抗体

反应种属

Human,Mouse,Rat

应用

WB,IHC-P,IF-ICC,IF-P

别名

MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4;

Clonality

Monoclonal

存储缓冲液

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

免疫原

A synthetic peptide of human MT4-MMP

稀释度

WB 1:1000, IHC-P/IF-P 1:100, IF-ICC 1:20-1:100

参考分子量

63kDa

预测分子量

67kDa

运输及保存条件

20°C/1 year

Human Gene ID

4326

基因名称

MMP17

蛋白名称

MT4MMP

宿主

Rabbit

同种型

LgG

组织表达

Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-\

transformed cell types

细胞定位

[Isoform Long]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side. Secreted, extracellular space, extracellular

matrix

注意事项

MMP17 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

功能

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation
of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be i
nvolved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activ
ate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha
1-antitrypsin.

                         

Western blot analysis of extracts from Mouse brain tissue using at 1:1000.

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process.

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