|
产品名称 |
EBP50 (15W12) Rabbit Monoclonal Antibody |
|
英文名称 |
EBP50 (15W12) Rabbit Monoclonal Antibody |
|
类别 |
抗原抗体 |
|
反应种属 |
Human,Rat |
|
应用 |
WB,IHC-P,IHC-F |
|
别名 |
SLC9A3R1; EBP50; NPHLOP2; NHERF; NHERF-1; NHERF1; |
|
Clonality |
Monoclonal |
|
存储缓冲液 |
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
|
稀释度 |
WB 1:1000-1:2000,IHC-P/IHC-F 1:100-1:200 |
|
运输及保存条件 |
20°C/1 year |
|
Human Gene ID |
9368 |
|
预测分子量 |
39kDa |
|
参考分子量 |
50kDa |
|
蛋白名称 |
NHERF, NHERF1 |
|
基因名称 |
SLC9A3R1 |
|
宿主 |
Rabbit |
|
同种型 |
LgG |
|
组织表达 |
Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast. |
|
细胞定位 |
Cytoplasm. Apical cell membrane. Endomembrane system; Peripheral membrane protein. Cell projection, filopodium. Cell pro jection, ruffle. Cell projection, microvillus. Note=Translocates from the cytoplasm to the apical cell membrane in a POD XL-dependent manner. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). Colocalizes with actin in micr ovilli-rich apical regions of the syncytiotrophoblast. Found in microvilli, ruffling membrane and filopodia of HeLa cell s. Present in lipid rafts of T-cells. |
|
注意事项 |
EBP50 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
|
功能 |
Scaffold protein that connects plasma membrane proteins with members of the family and thereby helps t |
 Rabbit Monoclonal Antibody.jpg)
Western blot analysis of EBP50 expression in (1) HepG2 cell lysate; (2) PC12 cell lysate.
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3.
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 Rabbit Monoclonal Antibody.jpg)
资料/datasheet
