
产品名称
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(Mouse) Bmi1 Rabbit Polyclonal Antibody (Center)
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英文名称
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(Mouse) Bmi1 Rabbit Polyclonal Antibody (Center)
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类别
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抗体产品
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反应种属
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Human, Mouse
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应用
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WB
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别名
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Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, Bmi1, Bmi-1, Pcgf4
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Clonality
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Polyclonal
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稀释度
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WB 1:2000
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预测分子量
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37kDa
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宿主
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Rabbit
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同种型
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IgG
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组织表达
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Detected in most organs with high expression levels in thymus, heart, brain and testis
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细胞定位
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Nucleus {ECO:0000250|UniProtKB:P35226}. Cytoplasm {ECO:0000250|UniProtKB:P35226}
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特异性
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This Mouse Bmi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptid
e between 109-143 amino acids from the Central region of Mouse Bmi1.
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背景介绍
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Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcription
ally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remod
eling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably
changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of
RNF2/RING2 (By similarity).
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 Bmi1 Rabbit Polyclonal Antibody (Center).jpg)
All lanes : Anti-Bmi1 Antibody (Center) at 1:2000 dilution Lane 1: NIH/3T3 whole cell lysates Lane 2: mouse kidney lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band
 Bmi1 Rabbit Polyclonal Antibody (Center).jpg)
Anti-Bmi1 Antibody (Center)at 1:2000 dilution + mouse heart lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.