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商品详情:
英文名称:FNDC5
中文名称:FNDC5单克隆抗体
别 名;Fibronectin type III domain containing 5; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat containing protein 2; Fibronectin type III repeat-containing protein 2; FNDC 5; FNDC5_HUMAN; FRCP2; Irisin.
研究领域;细胞生物 新陈代谢
抗体来源;Mouse
克隆类型;Monoclonal
克 隆 号F8U6
交叉反应; Human,
产品应用;WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量;12/20kDa
细胞定位;细胞浆 细胞膜 分泌型蛋白
性 状;Liquid
免 疫 原;KLH conjugated synthetic peptide derived from human FNDC5: 51-150/212 <Extracellular>
亚 型;IgG1,k
纯化方法;affinity purified by Protein G
缓 冲 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍; This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
Function:
Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.