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商品详情：
英文名称：FNBP4
中文名称：FNBP4蛋白抗体
别 名；DKFZp779I1064; FBP30; FNBP4_HUMAN; FLJ41904; FNBP 4; Formin binding protein 30; Formin binding protein 4; KIAA1014.
研究领域；肿瘤 细胞生物 免疫学 信号转导 结合蛋白 细胞骨架 新陈代谢
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用；ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量；110kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH conjugated synthetic peptide derived from human FNBP4: 921-1017/1017
亚 型；IgG
纯化方法；affinity purified by Protein A
缓 冲 液；0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍；FNBP4 is a 1,017 amino acid protein that contains two WW domains and binds to the Arg/Gly-rich-flanked Pro-rich domains of Formin 1, possibly regulating Formin 1 function. In response to DNA damage, FNBP4 is subject to post-translational phosphorylation, probably by ATM or ATR. The gene encoding FNBP4 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Function:
FNBP4 (Formin binding protein 4) binds FMN1. It contains 2 WW domains which interact with the Arg/Gly-rich-flanked Pro-rich domains of KHDRBS1/SAM68. Arginine methylation in these regions has no effect on this binding.
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资料/datasheet
