|
产品名称 |
IQGAP1 (14X7) Rabbit Monoclonal Antibody |
|
英文名称 |
IQGAP1 (14X7) Rabbit Monoclonal Antibody |
|
类别 |
抗原抗体 |
|
反应种属 |
Human |
|
应用 |
WB,IHC-P,IF-ICC,FCM,IF-P |
|
别名 |
Iqgap1; p195; SAR1; |
|
Clonality |
Monoclonal |
|
存储缓冲液 |
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
|
免疫原 |
A synthetic peptide of human IQGAP1 |
|
稀释度 |
WB 1:1000, IHC-P/IF-P 1:100-1:500, IF-ICC 1:100, FCM 1:20 |
|
参考分子量 |
189kDa |
|
预测分子量 |
189kDa |
|
运输及保存条件 |
20°C/1 year |
|
Human Gene ID |
8826 |
|
基因名称 |
IQGAP1 |
|
蛋白名称 |
KIAA0051 |
|
宿主 |
Rabbit |
|
同种型 |
LgG |
|
组织表达 |
Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas |
|
细胞定位 |
Cell membrane. Nucleus. Cytoplasm. Note=Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). |
|
注意事项 |
IQGAP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
|
功能 |
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not |
 Rabbit Monoclonal Antibody.jpg)
Western blot analysis of IQGAP1 expression in HeLa cell lysate.
Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane.
扫描二维码
扫描二维码
 Rabbit Monoclonal Antibody.jpg)
资料/datasheet
