|
产品名称 |
Claudin18.2(CLDN18.2) (7W11) Rabbit Monoclonal antibody |
|
英文名称 |
Claudin18.2(CLDN18.2) (7W11) Rabbit Monoclonal antibody |
|
类别 |
抗原抗体 |
|
反应种属 |
Human |
|
应用 |
IHC-P,IHC-F |
|
Clonality |
Monoclonal |
|
存储缓冲液 |
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N. |
|
稀释度 |
IHC-P/IHC-F 1:1000 |
|
预测分子量 |
27.5kDa |
|
运输及保存条件 |
20°C/1 year |
|
基因名称 |
Claudin18 |
|
免疫原 |
Human recombinant protein fragment of human Claudin18.2 ( NP_001002026) produced in E.coli. |
|
宿主 |
Rabbit |
|
同种型 |
LgG |
|
纯化 |
Affinity Purification |
|
背景介绍 |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands . Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] |
 (7W11) Rabbit Monoclonal antibody.jpg)
IHC staining of FFPE human gastric cancer tissue using anti-Claudin18.2(CLDN18.2) rabbit monoclonal antibody () and Polink-2 HRP polymer detection kit . Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 at 120°C for 3 min. The brown stai
 (7W11) Rabbit Monoclonal antibody.jpg)
IHC staining of FFPE human gastric tissue with in the normal limits using anti-Claudin18.2(CLDN18.2) rabbit monoclonal antibody () and Polink-2 HRP polymer detection kit . Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 at 120°C for 3
 (7W11) Rabbit Monoclonal antibody.jpg)
IHC staining of FFPE human lung tissue with in the normal limits using anti-Claudin18.2(CLDN18.2) rabbit monoclonal antibody () and Polink-2 HRP polymer detection kit . Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 at 120°C for 3 min
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 (7W11) Rabbit Monoclonal antibody.jpg)
 (7W11) Rabbit Monoclonal antibody.jpg)
 (7W11) Rabbit Monoclonal antibody.jpg)
资料/datasheet
