别名
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Matrix metalloproteinase-28, MMP-28, 3424-, Epilysin, MMP28, MMP25
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Clonality
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Polyclonal
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稀释度
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WB 1:1000, IHC-P 1:100-500
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预测分子量
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59kDa
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宿主
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Rabbit
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同种型
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LgG
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组织表达
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Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fet
al lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytes. Widely expressed in several carcinom
as as well. I
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细胞定位
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Secreted, extracellular space, extracellular matrix
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背景介绍
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both nor
mal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, s
uch as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests
that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have bee
n described. [provided by RefSeq].
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纯化
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein
A column, followed by peptide affinity purification.
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特异性
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This MMP28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acid
s from the Central region of human MMP28.
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