This KLF4 antibody is generated from a mouse immunized with a recombinant protein from the human reg
ion of human KLF4.
背景介绍
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promote
r region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors duri
ng embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiat
ion. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular
surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Cont
ributes to the down-regulation of p53/TP53 transcription.
All lanes : Anti-KLF4 Antibody at 1:500-1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: NCCIT whole cell lysate Lane 3: F9 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000